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Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Autophagy, the process by which proteins and organelles are sequestered in double-membrane structures called autophagosomes and delivered to lysosomes for degradation, is critical in diseases such as cancer and neurodegeneration(1,2). Much of our understanding of this process has emerged from analys...
Autores principales: | Mancias, Joseph D., Wang, Xiaoxu, Gygi, Steven P., Harper, J. Wade, Kimmelman, Alec C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180099/ https://www.ncbi.nlm.nih.gov/pubmed/24695223 http://dx.doi.org/10.1038/nature13148 |
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