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Lineage-specific adjacent IFNG and IL26 genes share a common distal enhancer element

Certain groups of physically linked genes remain linked over long periods of evolutionary time. The general view is that such evolutionary conservation confers ‘fitness’ to the species. Why gene order confers ‘fitness’ to the species is incompletely understood. For example, linkage of IL26 and IFNG...

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Detalles Bibliográficos
Autores principales:	Collins, Patrick L., Henderson, Melodie A., Aune, Thomas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180225/ https://www.ncbi.nlm.nih.gov/pubmed/22622197 http://dx.doi.org/10.1038/gene.2012.22

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