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1,25-Dihydroxyvitamin D3 increases testosterone-induced 17beta-estradiol secretion and reverses testosterone-reduced connexin 43 in rat granulosa cells

BACKGROUND: Aromatase converts testosterone into 17beta-estradiol in granulosa cells, and the converted 17beta-estradiol contributes to follicular maturation. Additionally, excessive testosterone inhibits aromatase activity, which can lead to concerns regarding polycystic ovary syndrome (PCOS). Gene...

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Detalles Bibliográficos
Autores principales:	Lee, Ching-Tien, Wang, Jiz-Yuh, Chou, Kuang-Yi, Hsu, Ming-I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180350/ https://www.ncbi.nlm.nih.gov/pubmed/25239217 http://dx.doi.org/10.1186/1477-7827-12-90

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