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Mitochondria-mediated apoptosis in mammals

The mitochondria-mediated caspase activation pathway is a major apoptotic pathway characterized by mitochondrial outer membrane permeabilization (MOMP) and subsequent release of cytochrome c into the cytoplasm to activate caspases. MOMP is regulated by the Bcl-2 family of proteins. This pathway play...

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Detalles Bibliográficos
Autores principales:	Xiong, Shunbin, Mu, Tianyang, Wang, Guowen, Jiang, Xuejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180462/ https://www.ncbi.nlm.nih.gov/pubmed/25073422 http://dx.doi.org/10.1007/s13238-014-0089-1

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