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Rheumatoid arthritis-associated aortitis: a case report and literature review

Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disorder that primarily affects the synovial joints. Rheumatoid vasculitis (RV) is an extra-articular manifestation of RA, and its association with aortitis is rare and not widely recognised. Here, we report the case of a 69-year-old wo...

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Autores principales: Kaneko, Shunta, Yamashita, Hiroyuki, Sugimori, Yusuke, Takahashi, Yuko, Kaneko, Hiroshi, Kano, Toshikazu, Mimori, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180505/
https://www.ncbi.nlm.nih.gov/pubmed/25279301
http://dx.doi.org/10.1186/2193-1801-3-509
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author Kaneko, Shunta
Yamashita, Hiroyuki
Sugimori, Yusuke
Takahashi, Yuko
Kaneko, Hiroshi
Kano, Toshikazu
Mimori, Akio
author_facet Kaneko, Shunta
Yamashita, Hiroyuki
Sugimori, Yusuke
Takahashi, Yuko
Kaneko, Hiroshi
Kano, Toshikazu
Mimori, Akio
author_sort Kaneko, Shunta
collection PubMed
description Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disorder that primarily affects the synovial joints. Rheumatoid vasculitis (RV) is an extra-articular manifestation of RA, and its association with aortitis is rare and not widely recognised. Here, we report the case of a 69-year-old woman with RA-associated aortitis and review the literature on rheumatoid aortitis. The mean oral steroid dose administered to RA-associated aortitis patients was 46.3 mg/day prednisolone (PSL). In our patient, the aortitis was also thought to be due to RV because she had findings of RV, such as cutaneous ulceration and a high rheumatoid factor titre, and because a moderate PSL dose dramatically improved the clinical findings. RA-associated aortitis, if left untreated, can be fatal; therefore, early detection and treatment initiation is very important.
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spelling pubmed-41805052014-10-02 Rheumatoid arthritis-associated aortitis: a case report and literature review Kaneko, Shunta Yamashita, Hiroyuki Sugimori, Yusuke Takahashi, Yuko Kaneko, Hiroshi Kano, Toshikazu Mimori, Akio Springerplus Case Study Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disorder that primarily affects the synovial joints. Rheumatoid vasculitis (RV) is an extra-articular manifestation of RA, and its association with aortitis is rare and not widely recognised. Here, we report the case of a 69-year-old woman with RA-associated aortitis and review the literature on rheumatoid aortitis. The mean oral steroid dose administered to RA-associated aortitis patients was 46.3 mg/day prednisolone (PSL). In our patient, the aortitis was also thought to be due to RV because she had findings of RV, such as cutaneous ulceration and a high rheumatoid factor titre, and because a moderate PSL dose dramatically improved the clinical findings. RA-associated aortitis, if left untreated, can be fatal; therefore, early detection and treatment initiation is very important. Springer International Publishing 2014-09-09 /pmc/articles/PMC4180505/ /pubmed/25279301 http://dx.doi.org/10.1186/2193-1801-3-509 Text en © Kaneko et al.; licensee Springer. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Case Study
Kaneko, Shunta
Yamashita, Hiroyuki
Sugimori, Yusuke
Takahashi, Yuko
Kaneko, Hiroshi
Kano, Toshikazu
Mimori, Akio
Rheumatoid arthritis-associated aortitis: a case report and literature review
title Rheumatoid arthritis-associated aortitis: a case report and literature review
title_full Rheumatoid arthritis-associated aortitis: a case report and literature review
title_fullStr Rheumatoid arthritis-associated aortitis: a case report and literature review
title_full_unstemmed Rheumatoid arthritis-associated aortitis: a case report and literature review
title_short Rheumatoid arthritis-associated aortitis: a case report and literature review
title_sort rheumatoid arthritis-associated aortitis: a case report and literature review
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180505/
https://www.ncbi.nlm.nih.gov/pubmed/25279301
http://dx.doi.org/10.1186/2193-1801-3-509
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