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Rheumatoid arthritis-associated aortitis: a case report and literature review
Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disorder that primarily affects the synovial joints. Rheumatoid vasculitis (RV) is an extra-articular manifestation of RA, and its association with aortitis is rare and not widely recognised. Here, we report the case of a 69-year-old wo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180505/ https://www.ncbi.nlm.nih.gov/pubmed/25279301 http://dx.doi.org/10.1186/2193-1801-3-509 |
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author | Kaneko, Shunta Yamashita, Hiroyuki Sugimori, Yusuke Takahashi, Yuko Kaneko, Hiroshi Kano, Toshikazu Mimori, Akio |
author_facet | Kaneko, Shunta Yamashita, Hiroyuki Sugimori, Yusuke Takahashi, Yuko Kaneko, Hiroshi Kano, Toshikazu Mimori, Akio |
author_sort | Kaneko, Shunta |
collection | PubMed |
description | Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disorder that primarily affects the synovial joints. Rheumatoid vasculitis (RV) is an extra-articular manifestation of RA, and its association with aortitis is rare and not widely recognised. Here, we report the case of a 69-year-old woman with RA-associated aortitis and review the literature on rheumatoid aortitis. The mean oral steroid dose administered to RA-associated aortitis patients was 46.3 mg/day prednisolone (PSL). In our patient, the aortitis was also thought to be due to RV because she had findings of RV, such as cutaneous ulceration and a high rheumatoid factor titre, and because a moderate PSL dose dramatically improved the clinical findings. RA-associated aortitis, if left untreated, can be fatal; therefore, early detection and treatment initiation is very important. |
format | Online Article Text |
id | pubmed-4180505 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-41805052014-10-02 Rheumatoid arthritis-associated aortitis: a case report and literature review Kaneko, Shunta Yamashita, Hiroyuki Sugimori, Yusuke Takahashi, Yuko Kaneko, Hiroshi Kano, Toshikazu Mimori, Akio Springerplus Case Study Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disorder that primarily affects the synovial joints. Rheumatoid vasculitis (RV) is an extra-articular manifestation of RA, and its association with aortitis is rare and not widely recognised. Here, we report the case of a 69-year-old woman with RA-associated aortitis and review the literature on rheumatoid aortitis. The mean oral steroid dose administered to RA-associated aortitis patients was 46.3 mg/day prednisolone (PSL). In our patient, the aortitis was also thought to be due to RV because she had findings of RV, such as cutaneous ulceration and a high rheumatoid factor titre, and because a moderate PSL dose dramatically improved the clinical findings. RA-associated aortitis, if left untreated, can be fatal; therefore, early detection and treatment initiation is very important. Springer International Publishing 2014-09-09 /pmc/articles/PMC4180505/ /pubmed/25279301 http://dx.doi.org/10.1186/2193-1801-3-509 Text en © Kaneko et al.; licensee Springer. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Case Study Kaneko, Shunta Yamashita, Hiroyuki Sugimori, Yusuke Takahashi, Yuko Kaneko, Hiroshi Kano, Toshikazu Mimori, Akio Rheumatoid arthritis-associated aortitis: a case report and literature review |
title | Rheumatoid arthritis-associated aortitis: a case report and literature review |
title_full | Rheumatoid arthritis-associated aortitis: a case report and literature review |
title_fullStr | Rheumatoid arthritis-associated aortitis: a case report and literature review |
title_full_unstemmed | Rheumatoid arthritis-associated aortitis: a case report and literature review |
title_short | Rheumatoid arthritis-associated aortitis: a case report and literature review |
title_sort | rheumatoid arthritis-associated aortitis: a case report and literature review |
topic | Case Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180505/ https://www.ncbi.nlm.nih.gov/pubmed/25279301 http://dx.doi.org/10.1186/2193-1801-3-509 |
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