Pharmacokinetic Study and Bioavailability of a Novel Synthetic Trioxane Antimalarial Compound 97/63 in Rats

Single dose pharmacokinetics study of 97/63 (IND191710, 2004), a trioxane antimalarial developed by Central Drug Research Institute, Lucknow, India, was studied in rats following intravenous and oral administration. Serum samples were analysed by HPLC-UV assay. Separation was achieved on a RP-18 col...

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Detalles Bibliográficos
Autores principales: Kushwaha, Hari Narayan, Mohan, Neel Kamal, Sharma, Ashok Kumar, Singh, Shio Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180634/
https://www.ncbi.nlm.nih.gov/pubmed/25302132
http://dx.doi.org/10.1155/2014/759392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180634/
https://www.ncbi.nlm.nih.gov/pubmed/25302132
http://dx.doi.org/10.1155/2014/759392

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