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SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells

Melanoma is one of the most aggressive types of human cancer, characterized by enhanced heterogeneity and resistance to conventional therapy at advanced stages. We and others have previously shown that HEDGEHOG-GLI (HH-GLI) signaling is required for melanoma growth and for survival and expansion of...

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Detalles Bibliográficos
Autores principales:	Santini, R, Pietrobono, S, Pandolfi, S, Montagnani, V, D'Amico, M, Penachioni, J Y, Vinci, M C, Borgognoni, L, Stecca, B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180644/ https://www.ncbi.nlm.nih.gov/pubmed/24681955 http://dx.doi.org/10.1038/onc.2014.71

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