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Downregulation of the Gli Transcription Factors Regulator Kif7 Facilitates Cell Survival and Migration of Choriocarcinoma Cells

The kinesin protein Kif7 has been recognized as an integral component of hedgehog signalling. Aberrant activation of hedgehog signalling has been implicated in many human solid tumours. Gestational trophoblastic disease includes frankly malignant choriocarcinoma and potentially malignant hydatidifor...

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Detalles Bibliográficos
Autores principales: Ho, Joanna, Du, Yanan, Wong, Oscar Gee-Wan, Siu, Michelle K. Y., Chan, Karen K. L., Cheung, Annie N. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180749/
https://www.ncbi.nlm.nih.gov/pubmed/25265279
http://dx.doi.org/10.1371/journal.pone.0108248