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Systemic NK cell ablation attenuates intra-abdominal adipose tissue macrophage infiltration in murine obesity

OBJECTIVE: NK cells are understudied in the context of metabolic disease and obesity. The goal of this study was to define the effect of NK cell ablation on systemic inflammation and glucose homeostasis in murine obesity. METHODS: A transgenic murine model was used to study the effect of NK cell abl...

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Detalles Bibliográficos
Autores principales: O’Rourke, Robert W., Meyer, Kevin A., Neeley, Christopher K., Gaston, Garen D., Sekhri, Palak, Szumowski, Marek, Zamarron, Brian, Lumeng, Carey N., Marks, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180782/
https://www.ncbi.nlm.nih.gov/pubmed/24962029
http://dx.doi.org/10.1002/oby.20823