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Cytokine response to selected MTB antigens in Ghanaian TB patients, before and at 2 weeks of anti-TB therapy is characterized by high expression of IFN-γ and Granzyme B and inter- individual variation

BACKGROUND: There has been a long held belief that patients with drug-susceptible TB are non-infectious after two weeks of therapy. Recent microbiological and epidemiological evidence has challenged this dogma, however, the nature of the Mtb-specific cellular immune response during this period has n...

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Detalles Bibliográficos
Autores principales: Mensah, Gloria Ivy, Addo, Kennedy Kwasi, Tetteh, John Amissah, Sowah, Sandra, Loescher, Thomas, Geldmacher, Christof, Jackson-Sillah, Dolly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180837/
https://www.ncbi.nlm.nih.gov/pubmed/25209422
http://dx.doi.org/10.1186/1471-2334-14-495