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Inhibition of long non-coding RNA NEAT1 impairs myeloid differentiation in acute promyelocytic leukemia cells

BACKGROUND: Acute promyelocytic leukemia (APL) is characterized by the reciprocal translocation t(15;17), which fuses PML with retinoic acid receptor alpha (RARα). Although PML-RARα is crucially important for pathogenesis and responsiveness to treatment, the molecular and cellular mechanisms by whic...

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Detalles Bibliográficos
Autores principales:	Zeng, Chengwu, Xu, Yan, Xu, Ling, Yu, Xibao, Cheng, Jingjing, Yang, Lijian, Chen, Shaohua, Li, Yangqiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180842/ https://www.ncbi.nlm.nih.gov/pubmed/25245097 http://dx.doi.org/10.1186/1471-2407-14-693

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