Magnetic Resonance Microscopy for Assessment of Morphological Changes in Hydrating Hydroxypropylmethylcellulose Matrix Tablets In Situ–Is it Possible to Detect Phenomena Related to Drug Dissolution Within the Hydrated Matrices?

PURPOSE: So far, the hydrated part of the HPMC matrix has commonly been denoted as a “gel” or “pseudogel” layer. No MRI-based results have been published regarding observation of internal phenomena related to drug dissolution inside swelling polymeric matrices during hydration. The purpose of the st...

Descripción completa

Detalles Bibliográficos
Autores principales: Kulinowski, Piotr, Młynarczyk, Anna, Jasiński, Krzysztof, Talik, Przemysław, Gruwel, Marco L. H., Tomanek, Bogusław, Węglarz, Władysław P., Dorożyński, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180912/
https://www.ncbi.nlm.nih.gov/pubmed/24633415
http://dx.doi.org/10.1007/s11095-014-1334-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180912/
https://www.ncbi.nlm.nih.gov/pubmed/24633415
http://dx.doi.org/10.1007/s11095-014-1334-2

Ejemplares similares