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Orbital rhabdomyosarcoma with skin metastasis: a case report

BACKGROUND: Rhabdomyosarcoma is a soft tissue neoplasm that usually arises in the headand neck region and genitourinary tract. Skin metastasis of rhabdomyosarcoma is extremely rare; of thirteen cases reported in the literature, most were children younger than 10 years and only three cases have been...

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Autores principales: Elomrani, Fadwa, Touri, Salima, Ouziane, Imane, Berrada, Narjiss, Boutayeb, Saber, Mrabti, Hind, Elkhannoussi, Basma, Errihani, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181003/
https://www.ncbi.nlm.nih.gov/pubmed/25253623
http://dx.doi.org/10.1186/1756-0500-7-670
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author Elomrani, Fadwa
Touri, Salima
Ouziane, Imane
Berrada, Narjiss
Boutayeb, Saber
Mrabti, Hind
Elkhannoussi, Basma
Errihani, Hassan
author_facet Elomrani, Fadwa
Touri, Salima
Ouziane, Imane
Berrada, Narjiss
Boutayeb, Saber
Mrabti, Hind
Elkhannoussi, Basma
Errihani, Hassan
author_sort Elomrani, Fadwa
collection PubMed
description BACKGROUND: Rhabdomyosarcoma is a soft tissue neoplasm that usually arises in the headand neck region and genitourinary tract. Skin metastasis of rhabdomyosarcoma is extremely rare; of thirteen cases reported in the literature, most were children younger than 10 years and only three cases have been reported in adults. CASE PRESENTATION: A 20-year-old Moroccan man was admitted with a right orbital tumor. The tumor was excised and histopathology examination confirmed a diagnosis of rhabdomyosarcoma. The patient was treated with chemotherapy, but local recurrence occurred one year later. The patient underwent right orbital exenteration followed by chemotherapy and radiotherapy. After 6 months, the patient developed a cutaneous mass in the right lumbar region, which was resected. Immunohistochemical examination of the tumor showed this to be a cutaneous metastasis of rhabdomyosarcoma. The patient was treated by chemotherapy and there appeared to be no recurrence after 9 months of follow up. CONCLUSIONS: Skin metastasis from rhabdomyosarcoma is extremely rare, particularly in adults. The purpose of presenting this case report is to raise awareness among clinicians— skin biopsy and immunohistochemistry are needed to distinguish this neoplasm from other cutaneous tumors so that appropriate treatment can be initiated.
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spelling pubmed-41810032014-10-03 Orbital rhabdomyosarcoma with skin metastasis: a case report Elomrani, Fadwa Touri, Salima Ouziane, Imane Berrada, Narjiss Boutayeb, Saber Mrabti, Hind Elkhannoussi, Basma Errihani, Hassan BMC Res Notes Case Report BACKGROUND: Rhabdomyosarcoma is a soft tissue neoplasm that usually arises in the headand neck region and genitourinary tract. Skin metastasis of rhabdomyosarcoma is extremely rare; of thirteen cases reported in the literature, most were children younger than 10 years and only three cases have been reported in adults. CASE PRESENTATION: A 20-year-old Moroccan man was admitted with a right orbital tumor. The tumor was excised and histopathology examination confirmed a diagnosis of rhabdomyosarcoma. The patient was treated with chemotherapy, but local recurrence occurred one year later. The patient underwent right orbital exenteration followed by chemotherapy and radiotherapy. After 6 months, the patient developed a cutaneous mass in the right lumbar region, which was resected. Immunohistochemical examination of the tumor showed this to be a cutaneous metastasis of rhabdomyosarcoma. The patient was treated by chemotherapy and there appeared to be no recurrence after 9 months of follow up. CONCLUSIONS: Skin metastasis from rhabdomyosarcoma is extremely rare, particularly in adults. The purpose of presenting this case report is to raise awareness among clinicians— skin biopsy and immunohistochemistry are needed to distinguish this neoplasm from other cutaneous tumors so that appropriate treatment can be initiated. BioMed Central 2014-09-24 /pmc/articles/PMC4181003/ /pubmed/25253623 http://dx.doi.org/10.1186/1756-0500-7-670 Text en © Elomrani et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Case Report
Elomrani, Fadwa
Touri, Salima
Ouziane, Imane
Berrada, Narjiss
Boutayeb, Saber
Mrabti, Hind
Elkhannoussi, Basma
Errihani, Hassan
Orbital rhabdomyosarcoma with skin metastasis: a case report
title Orbital rhabdomyosarcoma with skin metastasis: a case report
title_full Orbital rhabdomyosarcoma with skin metastasis: a case report
title_fullStr Orbital rhabdomyosarcoma with skin metastasis: a case report
title_full_unstemmed Orbital rhabdomyosarcoma with skin metastasis: a case report
title_short Orbital rhabdomyosarcoma with skin metastasis: a case report
title_sort orbital rhabdomyosarcoma with skin metastasis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181003/
https://www.ncbi.nlm.nih.gov/pubmed/25253623
http://dx.doi.org/10.1186/1756-0500-7-670
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