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Mutations in the Testis-Specific Enhancer of SOX9 in the SRY Independent Sex-Determining Mechanism in the Genus Tokudaia

SRY (sex-determining region Y) is widely conserved in eutherian mammals as a sex-determining gene located on the Y chromosome. SRY proteins bind to the testis-specific enhancer of SOX9 (TES) with SF1 to upregulate SOX9 expression in undifferentiated gonads of XY embryos of humans and mice. The core...

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Detalles Bibliográficos
Autores principales: Kimura, Ryutaro, Murata, Chie, Kuroki, Yoko, Kuroiwa, Asato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181316/
https://www.ncbi.nlm.nih.gov/pubmed/25265165
http://dx.doi.org/10.1371/journal.pone.0108779

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