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Long-term efficacy and safety of once-daily mesalazine granules for the treatment of active ulcerative colitis
In 1977, 5-aminosalicylic acid (5-ASA) was discovered as a therapeutically active moiety of sulfasalazine (SASP) and was launched for topical and oral therapy of ulcerative colitis (UC) in 1984. As a first-step, delivery systems had to be developed to protect 5-ASA against absorption in the upper ga...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181447/ https://www.ncbi.nlm.nih.gov/pubmed/25285021 http://dx.doi.org/10.2147/CEG.S35691 |