Use of a targeted, combinatorial next-generation sequencing approach for the study of bicuspid aortic valve

BACKGROUND: Bicuspid aortic valve (BAV) is the most common type of congenital heart disease with a population prevalence of 1-2%. While BAV is known to be highly heritable, mutations in single genes (such as GATA5 and NOTCH1) have been reported in few human BAV cases. Traditional gene sequencing met...

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Detalles Bibliográficos
Autores principales: Bonachea, Elizabeth M, Zender, Gloria, White, Peter, Corsmeier, Don, Newsom, David, Fitzgerald-Butt, Sara, Garg, Vidu, McBride, Kim L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181662/
https://www.ncbi.nlm.nih.gov/pubmed/25260786
http://dx.doi.org/10.1186/1755-8794-7-56

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