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Silk fibroin nanoparticles constitute a vector for controlled release of resveratrol in an experimental model of inflammatory bowel disease in rats
PURPOSE: We aimed to evaluate the intestinal anti-inflammatory properties of silk fibroin nanoparticles, around 100 nm in size, when loaded with the stilbene compound resveratrol, in an experimental model of rat colitis. METHODS: Nanoparticles were loaded with resveratrol by adsorption. The biologic...
Autores principales: | Lozano-Pérez, Antonio Abel, Rodriguez-Nogales, Alba, Ortiz-Cullera, Víctor, Algieri, Francesca, Garrido-Mesa, José, Zorrilla, Pedro, Rodriguez-Cabezas, M Elena, Garrido-Mesa, Natividad, Utrilla, M Pilar, De Matteis, Laura, de la Fuente, Jesús Martínez, Cenis, José Luis, Gálvez, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181735/ https://www.ncbi.nlm.nih.gov/pubmed/25285004 http://dx.doi.org/10.2147/IJN.S68526 |
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