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iStent trabecular micro-bypass stent for open-angle glaucoma

Trabecular micro-bypass stents, commonly known as iStents, are micro-invasive glaucoma surgery (MIGS) devices used to treat open-angle glaucoma. Like other MIGS procedures that enhance trabecular outflow, the iStent lowers intraocular pressure (IOP) by creating a direct channel between the anterior...

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Detalles Bibliográficos
Autores principales: Le, Kim, Saheb, Hady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181749/
https://www.ncbi.nlm.nih.gov/pubmed/25284980
http://dx.doi.org/10.2147/OPTH.S45920
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author Le, Kim
Saheb, Hady
author_facet Le, Kim
Saheb, Hady
author_sort Le, Kim
collection PubMed
description Trabecular micro-bypass stents, commonly known as iStents, are micro-invasive glaucoma surgery (MIGS) devices used to treat open-angle glaucoma. Like other MIGS procedures that enhance trabecular outflow, the iStent lowers intraocular pressure (IOP) by creating a direct channel between the anterior chamber and Schlemm’s canal. iStents are typically implanted at the time of phacoemulsification for patients with open-angle glaucoma and visually significant cataracts. This review summarizes the published data regarding the efficacy, safety, and cost considerations of trabecular micro-bypass stents. Most studies found statistically significant reductions in mean IOP and ocular medication use after combined phacoemulsification with single or double iStent implantation. The devices were found to be very safe, with a safety profile similar to that of cataract surgery. Complications were infrequent, with the most common complications being temporary stent obstruction or malposition, which resolved with observation or secondary procedures. Future studies are needed to evaluate long-term outcomes, patient satisfaction, cost effectiveness, and expanded indications.
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spelling pubmed-41817492014-10-03 iStent trabecular micro-bypass stent for open-angle glaucoma Le, Kim Saheb, Hady Clin Ophthalmol Review Trabecular micro-bypass stents, commonly known as iStents, are micro-invasive glaucoma surgery (MIGS) devices used to treat open-angle glaucoma. Like other MIGS procedures that enhance trabecular outflow, the iStent lowers intraocular pressure (IOP) by creating a direct channel between the anterior chamber and Schlemm’s canal. iStents are typically implanted at the time of phacoemulsification for patients with open-angle glaucoma and visually significant cataracts. This review summarizes the published data regarding the efficacy, safety, and cost considerations of trabecular micro-bypass stents. Most studies found statistically significant reductions in mean IOP and ocular medication use after combined phacoemulsification with single or double iStent implantation. The devices were found to be very safe, with a safety profile similar to that of cataract surgery. Complications were infrequent, with the most common complications being temporary stent obstruction or malposition, which resolved with observation or secondary procedures. Future studies are needed to evaluate long-term outcomes, patient satisfaction, cost effectiveness, and expanded indications. Dove Medical Press 2014-09-23 /pmc/articles/PMC4181749/ /pubmed/25284980 http://dx.doi.org/10.2147/OPTH.S45920 Text en © 2014 Le and Saheb. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Le, Kim
Saheb, Hady
iStent trabecular micro-bypass stent for open-angle glaucoma
title iStent trabecular micro-bypass stent for open-angle glaucoma
title_full iStent trabecular micro-bypass stent for open-angle glaucoma
title_fullStr iStent trabecular micro-bypass stent for open-angle glaucoma
title_full_unstemmed iStent trabecular micro-bypass stent for open-angle glaucoma
title_short iStent trabecular micro-bypass stent for open-angle glaucoma
title_sort istent trabecular micro-bypass stent for open-angle glaucoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181749/
https://www.ncbi.nlm.nih.gov/pubmed/25284980
http://dx.doi.org/10.2147/OPTH.S45920
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