Synaptojanin 1 Mutation in Parkinson's Disease Brings Further Insight into the Neuropathological Mechanisms

Synaptojanin 1 (SYNJ1) is a phosphoinositide phosphatase highly expressed in nerve terminals. Its two phosphatase domains dephosphorylate phosphoinositides present in membranes, while its proline-rich domain directs protein-protein interactions with synaptic components, leading to efficient recyclin...

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Detalles Bibliográficos
Autores principales: Drouet, Valérie, Lesage, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181773/
https://www.ncbi.nlm.nih.gov/pubmed/25302295
http://dx.doi.org/10.1155/2014/289728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181773/
https://www.ncbi.nlm.nih.gov/pubmed/25302295
http://dx.doi.org/10.1155/2014/289728

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