Cargando…

Fusion of CTLA-4 with HPV16 E7 and E6 Enhanced the Potency of Therapeutic HPV DNA Vaccine

Preventive anti-HPV vaccines are effective against HPV infection but not against existing HPV-associated diseases, including cervical cancer and other malignant diseases. Therefore, the development of therapeutic vaccines is urgently needed. To improve anti-tumor effects of therapeutic vaccine, we f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gan, Lili, Jia, Rong, Zhou, Lili, Guo, Jihua, Fan, Mingwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181872/ https://www.ncbi.nlm.nih.gov/pubmed/25265018 http://dx.doi.org/10.1371/journal.pone.0108892

Ejemplares similares

HPV16 E6/E7 -based mRNA vaccine is therapeutic in mice bearing aggressive HPV-positive lesions
por: Zhou, Kun, et al.
Publicado: (2023)

Diversity of cervicovaginal human papillomavirus (HPV) genotypes and naturally occurring E6/E7 DNA polymorphisms of HPV-16 in Ghana
por: Kaba, Gladys, et al.
Publicado: (2023)

Establishment of immunoassay for detecting HPV16 E6 and E7 RNA
por: Ding, Sen, et al.
Publicado: (2015)

Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine
por: Tseng, Ssu-Hsueh, et al.
Publicado: (2021)

A Non-oncogenic HPV 16 E6/E7 Vaccine Enhances Treatment of HPV Expressing Tumors
por: Wieking, Bryant G., et al.
Publicado: (2012)

E6/E7 and E6(*) From HPV16 and HPV18 Upregulate IL-6 Expression Independently of p53 in Keratinocytes
por: Artaza-Irigaray, Cristina, et al.
Publicado: (2019)

Identification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China
por: He, Jiaoyu, et al.
Publicado: (2019)

Augmentation of cellular and humoral immune responses to HPV16 and HPV18 E6 and E7 antigens by VGX-3100
por: Morrow, Matthew P, et al.
Publicado: (2016)

Brucella abortus RB51 lipopolysaccharide influence as an adjuvant on the therapeutic efficacy of HPV16 L1 and HPV16 E7 DNA vaccines
por: Shirmohammadi, Masoumeh, et al.
Publicado: (2021)

Sequential Cisplatin Therapy and Vaccination with HPV16 E6E7L2 Fusion Protein in Saponin Adjuvant GPI-0100 for the Treatment of a Model HPV16+ Cancer
por: Peng, Shiwen, et al.
Publicado: (2015)

Therapeutic vaccination using HPV 16 E7 to eradicate CIN3
por: Tewari, Krishnansu S.
Publicado: (2019)

HPV DNA methylation at the early promoter and E1/E2 integrity: A comparison between HPV16, HPV18 and HPV45 in cervical cancer
por: Amaro-Filho, Sérgio Menezes, et al.
Publicado: (2018)

Highly potent and specific siRNAs against E6 or E7 genes of HPV16- or HPV18-infected cervical cancers
por: Chang, J T-C, et al.
Publicado: (2010)

Short half‐life of HPV16 E6 and E7 mRNAs sensitizes HPV16‐positive tonsillar cancer cell line HN26 to DNA‐damaging drugs
por: Wu, Chengjun, et al.
Publicado: (2018)

Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody
por: Peng, Shiwen, et al.
Publicado: (2021)

HPV 16 E7 alters translesion synthesis signaling
por: Wendel, Sebastian O., et al.
Publicado: (2022)

Prognostic and diagnostic validity of p16/Ki-67, HPV E6/E7 mRNA, and HPV DNA in women with ASCUS: a follow-up study
por: Ren, Chenchen, et al.
Publicado: (2019)

Development and validation of a multiplex qPCR assay for detection and relative quantification of HPV16 and HPV18 E6 and E7 oncogenes
por: Bordigoni, Alexia, et al.
Publicado: (2021)

A novel HPV16 E7-affitoxin for targeted therapy of HPV16-induced human cervical cancer
por: Jiang, Pengfei, et al.
Publicado: (2018)

HPV16 E6 upregulates Aurora A expression
por: Guo, Yi, et al.
Publicado: (2016)

HPV genotype determination and E6/E7 mRNA detection for management of HPV positive women
por: Bruno, Maria Teresa, et al.
Publicado: (2018)

HPV16 E6 seropositivity among cancer-free men with oral, anal or genital HPV16 infection
por: Beachler, Daniel C., et al.
Publicado: (2016)

Attenuated Recombinant Influenza A Virus Expressing HPV16 E6 and E7 as a Novel Therapeutic Vaccine Approach
por: Jindra, Christoph, et al.
Publicado: (2015)

Design of a Highly Effective Therapeutic HPV16 E6/E7-Specific DNA Vaccine: Optimization by Different Ways of Sequence Rearrangements (Shuffling)
por: Almajhdi, Fahad N., et al.
Publicado: (2014)

Identification of novel HLA-A*11:01-restricted HPV16 E6/E7 epitopes and T-cell receptors for HPV-related cancer immunotherapy
por: Xiong, Chengjie, et al.
Publicado: (2022)

Association of cervical carcinogenesis risk with HPV16 E6 and E7 variants in the Taizhou area, China
por: Dai, Mei-Zhen, et al.
Publicado: (2021)

Immune responses, therapeutic anti-tumor effects, and tolerability upon therapeutic HPV16/18 E6/E7 DNA vaccination via needle-free biojector
por: Peng, Shiwen, et al.
Publicado: (2023)

Generation of affibody molecules specific for HPV16 E7 recognition
por: Xue, Xiangyang, et al.
Publicado: (2016)

Phylogeny and polymorphism in the E6 and E7 of human papillomavirus: alpha-9 (HPV16, 31, 33, 52, 58), alpha-5 (HPV51), alpha-6 (HPV53, 66), alpha-7 (HPV18, 39, 59, 68) and alpha-10 (HPV6, 44) in women from Shanghai
por: Zhao, Junwei, et al.
Publicado: (2019)

The Expression of HPV E6/E7 mRNA In Situ Hybridization in HPV Typing-negative Cervical Cancer
por: Xu, Yating, et al.
Publicado: (2023)

Performance of p16/Ki67 immunostaining, HPV E6/E7 mRNA testing, and HPV DNA assay to detect high-grade cervical dysplasia in women with ASCUS
por: Zhu, Yuanhang, et al.
Publicado: (2019)

Differential localization of HPV16 E6 splice products with E6-associated protein
por: Vaeteewoottacharn, Kulthida, et al.
Publicado: (2005)

Deep Sequencing of HPV16 E6 Region Reveals Unique Mutation Pattern of HPV16 and Predicts Cervical Cancer
por: Ai, Wenchao, et al.
Publicado: (2022)

The combined HPV16-E2/E6/E7 T cell response in oropharyngeal cancer predicts superior survival
por: Santegoets, Saskia J., et al.
Publicado: (2023)

Construction and detection of the tissue-specific pINV-HPV16 E6/7 vector
por: GAO, HUI, et al.
Publicado: (2015)

Development and validation of a multiplex immunoassay for the simultaneous quantification of type-specific IgG antibodies to E6/E7 oncoproteins of HPV16 and HPV18
por: Layman, Hans, et al.
Publicado: (2020)

Correction: Identification of novel HLA-A*11:01-restricted HPV16 E6/E7 epitopes and T-cell receptors for HPV-related cancer immunotherapy
Publicado: (2022)

Correction: Attenuated Recombinant Influenza A Virus Expressing HPV16 E6 and E7 as a Novel Therapeutic Vaccine Approach
por: Jindra, Christoph, et al.
Publicado: (2015)

Flavonol and imidazole derivatives block HPV16 E6 activities and reactivate apoptotic pathways in HPV(+) cells
por: Yuan, C-H, et al.
Publicado: (2016)

Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens
por: Arribillaga, Laura, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3f6gmor4edsf4r0r6kss0mq6un