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In Vivo Protection against Strychnine Toxicity in Mice by the Glycine Receptor Agonist Ivermectin
The inhibitory glycine receptor, a ligand-gated ion channel that mediates fast synaptic inhibition in mammalian spinal cord and brainstem, is potently and selectively inhibited by the alkaloid strychnine. The anthelminthic and anticonvulsant ivermectin is a strychnine-independent agonist of spinal g...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181905/ https://www.ncbi.nlm.nih.gov/pubmed/25317421 http://dx.doi.org/10.1155/2014/640790 |