HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy

Preeclampsia is a leading cause of maternal mortality and morbidity worldwide. The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality for women and their infants alike. Hormonal changes during pregnancy and the puerperium ca...

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Autores principales: Dag, Zeynep Ozcan, Işik, Yuksel, Simsek, Yavuz, Tulmac, Ozlem Banu, Demiray, Demet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182000/
https://www.ncbi.nlm.nih.gov/pubmed/25317347
http://dx.doi.org/10.1155/2014/582890
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author Dag, Zeynep Ozcan
Işik, Yuksel
Simsek, Yavuz
Tulmac, Ozlem Banu
Demiray, Demet
author_facet Dag, Zeynep Ozcan
Işik, Yuksel
Simsek, Yavuz
Tulmac, Ozlem Banu
Demiray, Demet
author_sort Dag, Zeynep Ozcan
collection PubMed
description Preeclampsia is a leading cause of maternal mortality and morbidity worldwide. The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality for women and their infants alike. Hormonal changes during pregnancy and the puerperium carry an increased risk of venous thromboembolism including cerebral venous sinus thrombosis (CVST). Factor 5 leiden (FVL) is a procoagulant mutation associated primarily with venous thrombosis and pregnancy complications. We report a patient with FVL mutation who presented with CVST at 24th week of pregnancy and was diagnosed as HELLP syndrome at 34th week of pregnancy.
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spelling pubmed-41820002014-10-14 HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy Dag, Zeynep Ozcan Işik, Yuksel Simsek, Yavuz Tulmac, Ozlem Banu Demiray, Demet Case Rep Obstet Gynecol Case Report Preeclampsia is a leading cause of maternal mortality and morbidity worldwide. The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality for women and their infants alike. Hormonal changes during pregnancy and the puerperium carry an increased risk of venous thromboembolism including cerebral venous sinus thrombosis (CVST). Factor 5 leiden (FVL) is a procoagulant mutation associated primarily with venous thrombosis and pregnancy complications. We report a patient with FVL mutation who presented with CVST at 24th week of pregnancy and was diagnosed as HELLP syndrome at 34th week of pregnancy. Hindawi Publishing Corporation 2014 2014-09-17 /pmc/articles/PMC4182000/ /pubmed/25317347 http://dx.doi.org/10.1155/2014/582890 Text en Copyright © 2014 Zeynep Ozcan Dag et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dag, Zeynep Ozcan
Işik, Yuksel
Simsek, Yavuz
Tulmac, Ozlem Banu
Demiray, Demet
HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_full HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_fullStr HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_full_unstemmed HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_short HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_sort hellp syndrome and cerebral venous sinus thrombosis associated with factor v leiden mutation during pregnancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182000/
https://www.ncbi.nlm.nih.gov/pubmed/25317347
http://dx.doi.org/10.1155/2014/582890
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