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In TFIIH, XPD Helicase Is Exclusively Devoted to DNA Repair

The eukaryotic XPD helicase is an essential subunit of TFIIH involved in both transcription and nucleotide excision repair (NER). Mutations in human XPD are associated with several inherited diseases such as xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy. We performed a comparativ...

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Detalles Bibliográficos
Autores principales: Kuper, Jochen, Braun, Cathy, Elias, Agnes, Michels, Gudrun, Sauer, Florian, Schmitt, Dominik R., Poterszman, Arnaud, Egly, Jean-Marc, Kisker, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182028/
https://www.ncbi.nlm.nih.gov/pubmed/25268380
http://dx.doi.org/10.1371/journal.pbio.1001954