Early Detection of Motor Dysfunction in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Using Home Cage Running Wheels

The SOD1(G93A) mouse has been used since 1994 for preclinical testing in amyotrophic lateral sclerosis (ALS). Despite recent genetic advances in our understanding of ALS, transgenic mice expressing mutant SOD1 remain the best available, and most widely used, vertebrate model of the disease. We previ...

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Detalles Bibliográficos
Autores principales: Bennett, Ellen J., Mead, Richard J., Azzouz, Mimoun, Shaw, Pamela J., Grierson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182307/
https://www.ncbi.nlm.nih.gov/pubmed/25268710
http://dx.doi.org/10.1371/journal.pone.0107918

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