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Regulation of the Mitogen Activated Protein Kinase Kinase (MEK)-1 by NAD(+)-Dependent Deacetylases
Sirtuins are class III deacetylases that regulate many essential processes, including cellular stress, genome stability, and metabolism. Although these NAD(+)-dependent deacetylases control adaptive cellular responses, identification of sirtuin-regulated signaling targets remain under-studied. Here,...
Autores principales: | Yeung, Fan, Ramsey, Catherine S., Popko-Scibor, Anita E., Allison, David F., Gray, Lisa G., Shin, Min, Kumar, Manish, Li, Duo, McCubrey, James A., Mayo, Marty W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182313/ https://www.ncbi.nlm.nih.gov/pubmed/24681949 http://dx.doi.org/10.1038/onc.2014.39 |
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