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Characterization of Niphatenones that Inhibit Androgen Receptor N-Terminal Domain

Androgen ablation therapy causes a temporary reduction in tumor burden in patients with advanced prostate cancer. Unfortunately the malignancy will return to form lethal castration-recurrent prostate cancer (CRPC). The androgen receptor (AR) remains transcriptionally active in CRPC in spite of castr...

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Detalles Bibliográficos
Autores principales: Banuelos, Carmen A., Lal, Aaron, Tien, Amy H., Shah, Neel, Yang, Yu Chi, Mawji, Nasrin R., Meimetis, Labros G., Park, Jacob, Kunzhong, Jian, Andersen, Raymond J., Sadar, Marianne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182434/
https://www.ncbi.nlm.nih.gov/pubmed/25268119
http://dx.doi.org/10.1371/journal.pone.0107991