Negative Regulation of Grb10 Interacting GYF Protein 2 on Insulin-Like Growth Factor-1 Receptor Signaling Pathway Caused Diabetic Mice Cognitive Impairment

Heterozygous Gigyf2 (+/−) mice exhibits histopathological evidence of neurodegeneration such as motor dysfunction. Several lines of evidence have demonstrated the important role of insulin-like growth factor-1 receptor (IGF1R) signaling pathway in the neuropathogenic process of cognitive impairment,...

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Detalles Bibliográficos
Autores principales: Xie, Jing, Wei, Qianping, Deng, Huacong, Li, Gang, Ma, Lingli, Zeng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182477/
https://www.ncbi.nlm.nih.gov/pubmed/25268761
http://dx.doi.org/10.1371/journal.pone.0108559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182477/
https://www.ncbi.nlm.nih.gov/pubmed/25268761
http://dx.doi.org/10.1371/journal.pone.0108559

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