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Persistent At-Level Thermal Hyperalgesia and Tactile Allodynia Accompany Chronic Neuronal and Astrocyte Activation in Superficial Dorsal Horn following Mouse Cervical Contusion Spinal Cord Injury
In humans, sensory abnormalities, including neuropathic pain, often result from traumatic spinal cord injury (SCI). SCI can induce cellular changes in the CNS, termed central sensitization, that alter excitability of spinal cord neurons, including those in the dorsal horn involved in pain transmissi...
Autores principales: | Watson, Jaime L., Hala, Tamara J., Putatunda, Rajarshi, Sannie, Daniel, Lepore, Angelo C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182513/ https://www.ncbi.nlm.nih.gov/pubmed/25268642 http://dx.doi.org/10.1371/journal.pone.0109099 |
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