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Identification of Essential Proteins Based on Ranking Edge-Weights in Protein-Protein Interaction Networks

Essential proteins are those that are indispensable to cellular survival and development. Existing methods for essential protein identification generally rely on knock-out experiments and/or the relative density of their interactions (edges) with other proteins in a Protein-Protein Interaction (PPI)...

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Detalles Bibliográficos
Autores principales:	Wang, Yan, Sun, Huiyan, Du, Wei, Blanzieri, Enrico, Viero, Gabriella, Xu, Ying, Liang, Yanchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182551/ https://www.ncbi.nlm.nih.gov/pubmed/25268881 http://dx.doi.org/10.1371/journal.pone.0108716

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