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Development of CpG-Oligodeoxynucleotides for Effective Activation of Rabbit TLR9 Mediated Immune Responses

CpG-oligodeoxynucleotides (CpG-ODN) are potent immune stimuli being developed for use as adjuvants in different species. Toll-like receptor 9 (TLR9) is the cellular receptor for CpG-ODN in mammalian cells. The CpG-ODN with 18–24 deoxynucleotides that are in current use for human and mouse cells, how...

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Detalles Bibliográficos
Autores principales: Chuang, Tsung-Hsien, Lai, Chao-Yang, Tseng, Ping-Hui, Yuan, Chiun-Jye, Hsu, Li-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182578/
https://www.ncbi.nlm.nih.gov/pubmed/25269083
http://dx.doi.org/10.1371/journal.pone.0108808