Cargando…
NR4A1 Promotes PDGF-BB-Induced Cell Colony Formation in Soft Agar
The fibroblast mitogen platelet-derived growth factor -BB (PDGF-BB) induces a transient expression of the orphan nuclear receptor NR4A1 (also named Nur77, TR3 or NGFIB). The aim of the present study was to investigate the pathways through which NR4A1 is induced by PDGF-BB and its functional role. We...
Autores principales: | Eger, Glenda, Papadopoulos, Natalia, Lennartsson, Johan, Heldin, Carl-Henrik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182636/ https://www.ncbi.nlm.nih.gov/pubmed/25269081 http://dx.doi.org/10.1371/journal.pone.0109047 |
Ejemplares similares
-
Deubiquitinating enzymes USP4 and USP17 finetune the trafficking of PDGFRβ and affect PDGF-BB-induced STAT3 signalling
por: Sarri, Niki, et al.
Publicado: (2022) -
SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation
por: Wang, Kehuan, et al.
Publicado: (2023) -
Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression
por: Tsioumpekou, Maria, et al.
Publicado: (2020) -
Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression: Erratum
por: Tsioumpekou, Maria, et al.
Publicado: (2020) -
PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element–modifying factor 1
por: Papadopoulos, Natalia, et al.
Publicado: (2018)