Towards standardisation of cell-free DNA measurement in plasma: controls for extraction efficiency, fragment size bias and quantification

Circulating cell-free DNA (cfDNA) is becoming an important clinical analyte for prenatal testing, cancer diagnosis and cancer monitoring. The extraction stage is critical in ensuring clinical sensitivity of analytical methods measuring minority nucleic acid fractions, such as foetal-derived sequence...

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Detalles Bibliográficos
Autores principales: Devonshire, Alison S., Whale, Alexandra S., Gutteridge, Alice, Jones, Gerwyn, Cowen, Simon, Foy, Carole A., Huggett, Jim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Paper in Forefront
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182654/
https://www.ncbi.nlm.nih.gov/pubmed/24853859
http://dx.doi.org/10.1007/s00216-014-7835-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182654/
https://www.ncbi.nlm.nih.gov/pubmed/24853859
http://dx.doi.org/10.1007/s00216-014-7835-3

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