Effects of Deletion of Mutant Huntingtin in Steroidogenic Factor 1 Neurons on the Psychiatric and Metabolic Phenotype in the BACHD Mouse Model of Huntington Disease

Psychiatric and metabolic features appear several years before motor disturbances in the neurodegenerative Huntington’s disease (HD), caused by an expanded CAG repeat in the huntingtin (HTT) gene. Although the mechanisms leading to these aspects are unknown, dysfunction in the hypothalamus, a brain...

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Detalles Bibliográficos
Autores principales: Baldo, Barbara, Cheong, Rachel Y., Petersén, Åsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182678/
https://www.ncbi.nlm.nih.gov/pubmed/25271967
http://dx.doi.org/10.1371/journal.pone.0107691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182678/
https://www.ncbi.nlm.nih.gov/pubmed/25271967
http://dx.doi.org/10.1371/journal.pone.0107691

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