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Bacteria-Based Analysis of HIV-1 Vpu Channel Activity

HIV-1 Vpu is a small, single-span membrane protein with two attributed functions that increase the virus' pathogenicity: degradation of CD4 and inactivation of BST-2. Vpu has also been shown to posses ion channel activity, yet no correlation has been found between this attribute and Vpu's...

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Detalles Bibliográficos
Autores principales: Taube, Robert, Alhadeff, Raphael, Assa, Dror, Krugliak, Miriam, Arkin, Isaiah T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182682/
https://www.ncbi.nlm.nih.gov/pubmed/25272035
http://dx.doi.org/10.1371/journal.pone.0105387