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Hypogammaglobulinemia in BLT Humanized Mice – An Animal Model of Primary Antibody Deficiency
Primary antibody deficiencies present clinically as reduced or absent plasma antibodies without another identified disorder that could explain the low immunoglobulin levels. Bone marrow-liver-thymus (BLT) humanized mice also exhibit primary antibody deficiency or hypogammaglobulinemia. Comprehensive...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182704/ https://www.ncbi.nlm.nih.gov/pubmed/25271886 http://dx.doi.org/10.1371/journal.pone.0108663 |