Hypogammaglobulinemia in BLT Humanized Mice – An Animal Model of Primary Antibody Deficiency

Primary antibody deficiencies present clinically as reduced or absent plasma antibodies without another identified disorder that could explain the low immunoglobulin levels. Bone marrow-liver-thymus (BLT) humanized mice also exhibit primary antibody deficiency or hypogammaglobulinemia. Comprehensive...

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Detalles Bibliográficos
Autores principales: Martinez-Torres, Francisco, Nochi, Tomonori, Wahl, Angela, Garcia, J. Victor, Denton, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182704/
https://www.ncbi.nlm.nih.gov/pubmed/25271886
http://dx.doi.org/10.1371/journal.pone.0108663

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