Cargando…

Disc1 Variation Leads to Specific Alterations in Adult Neurogenesis

Disrupted in schizophrenia 1 (DISC1) is a risk factor for a spectrum of neuropsychiatric illnesses including schizophrenia, bipolar disorder, and major depressive disorder. Here we use two missense Disc1 mouse mutants, described previously with distinct behavioural phenotypes, to demonstrate that Di...

Descripción completa

Detalles Bibliográficos
Autores principales: Chandran, Jayanth S., Kazanis, Ilias, Clapcote, Steven J., Ogawa, Fumiaki, Millar, J. Kirsty, Porteous, David J., ffrench-Constant, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182707/
https://www.ncbi.nlm.nih.gov/pubmed/25272038
http://dx.doi.org/10.1371/journal.pone.0108088