Cargando…
Disc1 Variation Leads to Specific Alterations in Adult Neurogenesis
Disrupted in schizophrenia 1 (DISC1) is a risk factor for a spectrum of neuropsychiatric illnesses including schizophrenia, bipolar disorder, and major depressive disorder. Here we use two missense Disc1 mouse mutants, described previously with distinct behavioural phenotypes, to demonstrate that Di...
Autores principales: | Chandran, Jayanth S., Kazanis, Ilias, Clapcote, Steven J., Ogawa, Fumiaki, Millar, J. Kirsty, Porteous, David J., ffrench-Constant, Charles |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182707/ https://www.ncbi.nlm.nih.gov/pubmed/25272038 http://dx.doi.org/10.1371/journal.pone.0108088 |
Ejemplares similares
-
DISC1 variants 37W and 607F disrupt its nuclear targeting and regulatory role in ATF4-mediated transcription
por: Malavasi, Elise L.V., et al.
Publicado: (2012) -
The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche()
por: Kazanis, Ilias, et al.
Publicado: (2013) -
Hippocampal Neurogenesis Requires Cell-Autonomous Thyroid Hormone Signaling
por: Mayerl, Steffen, et al.
Publicado: (2020) -
Perspectives on disrupted-inschizophrenia 1 signaling in neurogenesis
por: Chandran, Jayanth S.
Publicado: (2015) -
DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking
por: Ogawa, Fumiaki, et al.
Publicado: (2014)