Prevention of Immune Nephritis by the Small Molecular Weight Immunomodulator Iguratimod in MRL/lpr Mice

OBJECTIVE: This study was performed to investigate the therapeutic effects of iguratimod in a lupus mouse model. METHODS: Female MRL/lpr mice were treated with iguratimod, vehicle solution or cyclophosphamide. Proteinuria was monitored and kidney injury was blindly scored by a renal pathologist. Ser...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Qingran, Du, Fang, Huang, Xinfang, Fu, Qiong, Chen, Sheng, Dai, Dai, Bao, Chunde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182720/
https://www.ncbi.nlm.nih.gov/pubmed/25271634
http://dx.doi.org/10.1371/journal.pone.0108273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182720/
https://www.ncbi.nlm.nih.gov/pubmed/25271634
http://dx.doi.org/10.1371/journal.pone.0108273

Ejemplares similares