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Prevention of Immune Nephritis by the Small Molecular Weight Immunomodulator Iguratimod in MRL/lpr Mice

OBJECTIVE: This study was performed to investigate the therapeutic effects of iguratimod in a lupus mouse model. METHODS: Female MRL/lpr mice were treated with iguratimod, vehicle solution or cyclophosphamide. Proteinuria was monitored and kidney injury was blindly scored by a renal pathologist. Ser...

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Detalles Bibliográficos
Autores principales:	Yan, Qingran, Du, Fang, Huang, Xinfang, Fu, Qiong, Chen, Sheng, Dai, Dai, Bao, Chunde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182720/ https://www.ncbi.nlm.nih.gov/pubmed/25271634 http://dx.doi.org/10.1371/journal.pone.0108273

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