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IL-6 Amplifies TLR Mediated Cytokine and Chemokine Production: Implications for the Pathogenesis of Rheumatic Inflammatory Diseases
The role of Interleukin(IL)-6 in the pathogenesis of joint and systemic inflammation in rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis (s-JIA) has been clearly demonstrated. However, the mechanisms by which IL-6 contributes to the pathogenesis are not completely understood. Thi...
Autores principales: | Caiello, Ivan, Minnone, Gaetana, Holzinger, Dirk, Vogl, Thomas, Prencipe, Giusi, Manzo, Antonio, De Benedetti, Fabrizio, Strippoli, Raffaele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182736/ https://www.ncbi.nlm.nih.gov/pubmed/25271853 http://dx.doi.org/10.1371/journal.pone.0107886 |
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