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Calcium-Activated Potassium Current Modulates Ventricular Repolarization in Chronic Heart Failure

The role of I(KCa) in cardiac repolarization remains controversial and varies across species. The relevance of the current as a therapeutic target is therefore undefined. We examined the cellular electrophysiologic effects of I(KCa) blockade in controls, chronic heart failure (HF) and HF with sustai...

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Detalles Bibliográficos
Autores principales: Bonilla, Ingrid M., Long, Victor P., Vargas-Pinto, Pedro, Wright, Patrick, Belevych, Andriy, Lou, Qing, Mowrey, Kent, Yoo, Jae, Binkley, Philip F., Fedorov, Vadim V., Györke, Sandor, Janssen, Paulus M. L., Kilic, Ahmet, Mohler, Peter J., Carnes, Cynthia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182742/
https://www.ncbi.nlm.nih.gov/pubmed/25271970
http://dx.doi.org/10.1371/journal.pone.0108824