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Calcium-Activated Potassium Current Modulates Ventricular Repolarization in Chronic Heart Failure
The role of I(KCa) in cardiac repolarization remains controversial and varies across species. The relevance of the current as a therapeutic target is therefore undefined. We examined the cellular electrophysiologic effects of I(KCa) blockade in controls, chronic heart failure (HF) and HF with sustai...
Autores principales: | Bonilla, Ingrid M., Long, Victor P., Vargas-Pinto, Pedro, Wright, Patrick, Belevych, Andriy, Lou, Qing, Mowrey, Kent, Yoo, Jae, Binkley, Philip F., Fedorov, Vadim V., Györke, Sandor, Janssen, Paulus M. L., Kilic, Ahmet, Mohler, Peter J., Carnes, Cynthia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182742/ https://www.ncbi.nlm.nih.gov/pubmed/25271970 http://dx.doi.org/10.1371/journal.pone.0108824 |
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