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Intra-Lesional Injection of the Novel PKC Activator EBC-46 Rapidly Ablates Tumors in Mouse Models

Intra-lesional chemotherapy for treatment of cutaneous malignancies has been used for many decades, allowing higher local drug concentrations and less toxicity than systemic agents. Here we describe a novel diterpene ester, EBC-46, and provide preclinical data supporting its use as an intra-lesional...

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Detalles Bibliográficos
Autores principales:	Boyle, Glen M., D'Souza, Marjorie M. A., Pierce, Carly J., Adams, Ryan A., Cantor, Aaron S., Johns, Jenny P., Maslovskaya, Lidia, Gordon, Victoria A., Reddell, Paul W., Parsons, Peter G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182759/ https://www.ncbi.nlm.nih.gov/pubmed/25272271 http://dx.doi.org/10.1371/journal.pone.0108887

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