The Polyphenols (−)-Epigallocatechin-3-Gallate and Luteolin Synergistically Inhibit TGF-β-Induced Myofibroblast Phenotypes through RhoA and ERK Inhibition

The presence of reactive stroma, predominantly composed of myofibroblasts, is directly associated with and drives prostate cancer progression. We have previously shown that (−)-Epigallocatechin-3-gallate (EGCG), in the form of Polyphenon E, significantly decreases serum levels of HGF and VEGF in pro...

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Detalles Bibliográficos
Autores principales: Gray, Alana L., Stephens, Charles A., Bigelow, Rebecca L. H., Coleman, David T., Cardelli, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182889/
https://www.ncbi.nlm.nih.gov/pubmed/25272043
http://dx.doi.org/10.1371/journal.pone.0109208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182889/
https://www.ncbi.nlm.nih.gov/pubmed/25272043
http://dx.doi.org/10.1371/journal.pone.0109208

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