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Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs

OBJECTIVE: In preterm newborn infants transfused with erythrocytes stored up to 28 days, to compare the reduction of blood donor exposure in two groups of infants classified according to birth weight. METHODS: A prospective study was conducted with preterm infants with birth weight <1000g (Group...

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Autores principales: Uezima, Cristina Lika, Barreto, Ariane Moreira, Guinsburg, Ruth, Chiba, Akemi Kuroda, Bordin, José Orlando, Barros, Melca Maria O., dos Santos, Amélia Miyashiro N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade de Pediatria de São Paulo 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182979/
https://www.ncbi.nlm.nih.gov/pubmed/24142309
http://dx.doi.org/10.1590/S0103-05822013000300003
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author Uezima, Cristina Lika
Barreto, Ariane Moreira
Guinsburg, Ruth
Chiba, Akemi Kuroda
Bordin, José Orlando
Barros, Melca Maria O.
dos Santos, Amélia Miyashiro N.
author_facet Uezima, Cristina Lika
Barreto, Ariane Moreira
Guinsburg, Ruth
Chiba, Akemi Kuroda
Bordin, José Orlando
Barros, Melca Maria O.
dos Santos, Amélia Miyashiro N.
author_sort Uezima, Cristina Lika
collection PubMed
description OBJECTIVE: In preterm newborn infants transfused with erythrocytes stored up to 28 days, to compare the reduction of blood donor exposure in two groups of infants classified according to birth weight. METHODS: A prospective study was conducted with preterm infants with birth weight <1000g (Group 1) and 1000-1499g (Group 2), born between April, 2008 and December, 2009. Neonates submitted to exchange transfusions, emergency erythrocyte transfusion, or those who died in the first 24 hours of life were excluded. Transfusions were indicated according to the local guideline using pediatric transfusion satellite bags. Demographic and clinical data, besides number of transfusions and donors were assessed. . Logistic regression analysis was performed to determine factors associated with multiple transfusions. RESULTS: 30 and 48 neonates were included in Groups 1 and 2, respectively. The percentage of newborns with more than one erythrocyte transfusion (90 versus 11%), the median number of transfusions (3 versus 1) and the median of blood donors (2 versus 1) were higher in Group 1 (p<0.001), compared to Group 2. Among those with multiple transfusions, 14 (82%) and one (50%) presented 50% reduction in the number of blood donors, respectively in Groups 1 and 2. Factors associated with multiple transfusions were: birth weight <1000g (OR 11.91; 95%CI 2.14-66.27) and presence of arterial umbilical catheter (OR 8.59; 95%CI 1.94-38.13), adjusted for confounders. CONCLUSIONS: The efficacy of pediatrics satellites bags on blood donor reduction was higher in preterm infants with birth weight <1000g.
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spelling pubmed-41829792014-10-14 Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs Uezima, Cristina Lika Barreto, Ariane Moreira Guinsburg, Ruth Chiba, Akemi Kuroda Bordin, José Orlando Barros, Melca Maria O. dos Santos, Amélia Miyashiro N. Rev Paul Pediatr Original Article OBJECTIVE: In preterm newborn infants transfused with erythrocytes stored up to 28 days, to compare the reduction of blood donor exposure in two groups of infants classified according to birth weight. METHODS: A prospective study was conducted with preterm infants with birth weight <1000g (Group 1) and 1000-1499g (Group 2), born between April, 2008 and December, 2009. Neonates submitted to exchange transfusions, emergency erythrocyte transfusion, or those who died in the first 24 hours of life were excluded. Transfusions were indicated according to the local guideline using pediatric transfusion satellite bags. Demographic and clinical data, besides number of transfusions and donors were assessed. . Logistic regression analysis was performed to determine factors associated with multiple transfusions. RESULTS: 30 and 48 neonates were included in Groups 1 and 2, respectively. The percentage of newborns with more than one erythrocyte transfusion (90 versus 11%), the median number of transfusions (3 versus 1) and the median of blood donors (2 versus 1) were higher in Group 1 (p<0.001), compared to Group 2. Among those with multiple transfusions, 14 (82%) and one (50%) presented 50% reduction in the number of blood donors, respectively in Groups 1 and 2. Factors associated with multiple transfusions were: birth weight <1000g (OR 11.91; 95%CI 2.14-66.27) and presence of arterial umbilical catheter (OR 8.59; 95%CI 1.94-38.13), adjusted for confounders. CONCLUSIONS: The efficacy of pediatrics satellites bags on blood donor reduction was higher in preterm infants with birth weight <1000g. Sociedade de Pediatria de São Paulo 2013-09 /pmc/articles/PMC4182979/ /pubmed/24142309 http://dx.doi.org/10.1590/S0103-05822013000300003 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Uezima, Cristina Lika
Barreto, Ariane Moreira
Guinsburg, Ruth
Chiba, Akemi Kuroda
Bordin, José Orlando
Barros, Melca Maria O.
dos Santos, Amélia Miyashiro N.
Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs
title Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs
title_full Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs
title_fullStr Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs
title_full_unstemmed Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs
title_short Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs
title_sort reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182979/
https://www.ncbi.nlm.nih.gov/pubmed/24142309
http://dx.doi.org/10.1590/S0103-05822013000300003
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