Role of adenosine in the antiepileptic effects of deep brain stimulation

Despite the effectiveness of anterior thalamic nucleus (AN) deep brain stimulation (DBS) for the treatment of epilepsy, mechanisms responsible for the antiepileptic effects of this therapy remain elusive. As adenosine modulates neuronal excitability and seizure activity in animal models, we hypothes...

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Detalles Bibliográficos
Autores principales: Miranda, Maisa F., Hamani, Clement, de Almeida, Antônio-Carlos G., Amorim, Beatriz O., Macedo, Carlos E., Fernandes, Maria José S., Nobrega, José N., Aarão, Mayra C., Madureira, Ana Paula, Rodrigues, Antônio M., Andersen, Monica L., Tufik, Sergio, Mello, Luiz E., Covolan, Luciene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183090/
https://www.ncbi.nlm.nih.gov/pubmed/25324724
http://dx.doi.org/10.3389/fncel.2014.00312

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