TGF-β co-opts STAT3-STAT4 signaling to promote human T follicular helper cell differentiation

Understanding the developmental mechanisms of T follicular helper (T(FH)) cells in humans is a highly relevant topic to clinic. However, factors that drive human CD4(+) helper T (T(H)) cell differentiation program towards T(FH) cells remain largely undefined. Here we show that TGF-β provides critica...

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Detalles Bibliográficos
Autores principales: Schmitt, Nathalie, Liu, Yang, Bentebibel, Salah-Eddine, Munagala, Indira, Bourdery, Laure, Venuprasad, K, Banchereau, Jacques, Ueno, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183221/
https://www.ncbi.nlm.nih.gov/pubmed/25064073
http://dx.doi.org/10.1038/ni.2947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183221/
https://www.ncbi.nlm.nih.gov/pubmed/25064073
http://dx.doi.org/10.1038/ni.2947

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