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TGF-β co-opts STAT3-STAT4 signaling to promote human T follicular helper cell differentiation

Understanding the developmental mechanisms of T follicular helper (T(FH)) cells in humans is a highly relevant topic to clinic. However, factors that drive human CD4(+) helper T (T(H)) cell differentiation program towards T(FH) cells remain largely undefined. Here we show that TGF-β provides critica...

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Detalles Bibliográficos
Autores principales:	Schmitt, Nathalie, Liu, Yang, Bentebibel, Salah-Eddine, Munagala, Indira, Bourdery, Laure, Venuprasad, K, Banchereau, Jacques, Ueno, Hideki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183221/ https://www.ncbi.nlm.nih.gov/pubmed/25064073 http://dx.doi.org/10.1038/ni.2947

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