Polymorphisms in Plasmodium falciparum Chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors that Affect Treatment Outcomes for P. falciparum Malaria after Artemether-Lumefantrine and Artesunate-Amodiaquine

Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P. falciparum multidrug resistance 1 (pfmdr1) genes are associated with de...

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Detalles Bibliográficos
Autores principales: Venkatesan, Meera, Gadalla, Nahla B., Stepniewska, Kasia, Dahal, Prabin, Nsanzabana, Christian, Moriera, Clarissa, Price, Ric N., Mårtensson, Andreas, Rosenthal, Philip J., Dorsey, Grant, Sutherland, Colin J., Guérin, Philippe, Davis, Timothy M. E., Ménard, Didier, Adam, Ishag, Ademowo, George, Arze, Cesar, Baliraine, Frederick N., Berens-Riha, Nicole, Björkman, Anders, Borrmann, Steffen, Checchi, Francesco, Desai, Meghna, Dhorda, Mehul, Djimdé, Abdoulaye A., El-Sayed, Badria B., Eshetu, Teferi, Eyase, Frederick, Falade, Catherine, Faucher, Jean-François, Fröberg, Gabrielle, Grivoyannis, Anastasia, Hamour, Sally, Houzé, Sandrine, Johnson, Jacob, Kamugisha, Erasmus, Kariuki, Simon, Kiechel, Jean-René, Kironde, Fred, Kofoed, Poul-Erik, LeBras, Jacques, Malmberg, Maja, Mwai, Leah, Ngasala, Billy, Nosten, Francois, Nsobya, Samuel L., Nzila, Alexis, Oguike, Mary, Otienoburu, Sabina Dahlström, Ogutu, Bernhards, Ouédraogo, Jean-Bosco, Piola, Patrice, Rombo, Lars, Schramm, Birgit, Somé, A. Fabrice, Thwing, Julie, Ursing, Johan, Wong, Rina P. M., Zeynudin, Ahmed, Zongo, Issaka, Plowe, Christopher V., Sibley, Carol Hopkins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183414/
https://www.ncbi.nlm.nih.gov/pubmed/25048375
http://dx.doi.org/10.4269/ajtmh.14-0031

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